Immunotherapy Allergy Treatment in Singapore

An allergy is an exaggerated immune response to substances that are usually harmless, known as allergens. Common allergens include pollen, dust mites, pet dander, mould, insect stings, medications, latex, and certain foods such as peanuts, shellfish, or dairy.

When an allergic person is exposed to an allergen, the immune system produces immunoglobulin E (IgE) antibodies, triggering the release of histamine and other inflammatory chemicals. This causes symptoms such as:

  • Sneezing and nasal congestion
  • Itchy or watery eyes
  • Skin rashes or hives
  • Swelling of the face, lips, tongue, or throat
  • Wheezing or difficulty breathing
  • Digestive symptoms in food-related allergies

In rare cases, severe reactions such as anaphylaxis may occur, requiring immediate treatment with epinephrine.

While medications like antihistamines and nasal corticosteroids can relieve symptoms, they do not address the underlying allergic response. Allergy immunotherapy is a medically proven treatment that gradually retrains the immune system to reduce sensitivity to allergens, providing long-term relief. Offered at a trusted ENT Clinic in Singapore, immunotherapy is carefully prescribed and monitored to help patients achieve sustained control over conditions such as allergic rhinitis, dust mite allergy, and pollen sensitivity.

How Immunotherapy Re-Trains the Immune System

Allergy immunotherapy works by gradually exposing the immune system to controlled amounts of the allergen, which helps reduce overreaction and inflammation over time.

  • Reduces IgE-mediated reactions
  • Promotes immune tolerance to allergens
  • Provides long-term symptom improvement beyond medication relief

Unlike short-term treatments, immunotherapy modifies the underlying allergic response rather than just suppressing symptoms.

Conditions Commonly Treated With Immunotherapy

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Allergy immunotherapy is used to manage persistent or difficult-to-control allergic conditions. Commonly treated conditions include:

  • Allergic rhinitis or hay fever
  • Dust mite allergy
  • Pollen allergy
  • Pet dander allergy
  • Selected cases of allergic asthma linked to airborne allergens

Allergy Testing Before Immunotherapy

Accurate allergy testing is essential to identify the allergens triggering symptoms. Tests may include:

  • Skin prick testing
  • Blood tests for IgE antibodies

This ensures treatment is personalised, safe, and effective. Patients can consult an allergy doctor in Singapore for diagnosis and treatment planning.

Types of Allergy Immunotherapy

There are two main forms of allergy immunotherapy, each designed to gradually reduce immune sensitivity. The choice of treatment depends on the allergen involved, medical suitability, and patient preference.

Subcutaneous Immunotherapy (SCIT) – Allergy Shots

  • Administered in a clinical setting
  • Starts with low doses, gradually increasing to a maintenance dose
  • Typically given monthly during the maintenance phase for 3+ years

Sublingual Immunotherapy (SLIT) – Allergy Tablets

  • Taken daily under the tongue at home after an initial supervised dose
  • Needle-free alternative
  • Suitable for patients who prefer home administration

Allergy Shots vs Sublingual Immunotherapy

Understanding the differences between these treatment options helps patients choose the best approach.

  • Allergy Shots (Subcutaneous Immunotherapy – SCIT): Administered in a clinic, starting with low doses and increasing to a maintenance dose, usually given monthly for several years.

  • Sublingual Immunotherapy (SLIT): Taken daily under the tongue at home after an initial supervised dose, providing a needle-free alternative for selected patients.

Both are effective under specialist guidance and monitoring.

The Role of ENT Specialists in Allergy Immunotherapy

ENT specialists assess nasal, sinus, and airway health, ensuring immunotherapy is safe, especially for patients with:

  • Asthma
  • Chronic sinus issues
  • Structural nasal abnormalities

They monitor treatment, adjust dosing, and manage side effects for optimal outcomes.

Who Is a Suitable Candidate for Immunotherapy?

Immunotherapy is most beneficial for patients with confirmed allergies who continue to experience symptoms despite conventional treatments.

  • Experience persistent symptoms despite medication
  • Have allergen exposure that cannot be avoided
  • Prefer a long-term, disease-modifying treatment

A thorough assessment by an ENT specialist or allergy doctor is essential.

What to Expect During Treatment

Understanding the treatment process helps patients stay informed and committed.

Treatment generally involves two phases:

  1. Build-up Phase
  • Doses start low and gradually increase
  • Usually lasts several months
  1. Maintenance Phase
  • Fixed dose administered regularly for up to three years
  • Symptoms gradually improve, with reduced reliance on medications
  • Patients are monitored throughout to ensure safety and efficacy.

Safety, Monitoring, and Side Effects

Allergy immunotherapy is generally safe when administered under specialist supervision. 

Common side effects include:

  • Mild redness or swelling at injection sites
  • Temporary mouth or throat irritation with SLIT

Rarely, systemic reactions such as anaphylaxis can occur. Patients are closely monitored, particularly during early treatment phases.

Long-Term Benefits of Allergy Immunotherapy

A woman sleeping comfortably on a pillow

By addressing the underlying allergic response rather than just suppressing symptoms, allergy immunotherapy offers benefits that extend well beyond short-term relief.

Patients may experience:

  • Reduced reliance on allergy medications
  • Sustained improvement in allergy symptoms even after treatment completion
  • Lower risk of developing new allergies or worsening asthma
  • Improved sleep quality, daily functioning, and overall quality of life

For patients considering a long-term solution to persistent allergies, personalised guidance is essential. You may speak to an ENT specialist to discuss whether allergy immunotherapy is suitable for your condition and treatment goals.

Trusted Resources for ENT Care in Singapore

Book Your Appointment with an ENT Specialist for Allergy

Book your appointment with our MOH‑registered ENT specialists at Mt Elizabeth Medical Centre, Orchard Road, Singapore, and receive expert, personalised allergy and immunotherapy care. Take the first step towards long‑term relief and improved well-being today.

Frequently Asked Questions

Allergy immunotherapy gradually retrains the immune system to reduce sensitivity to allergens, providing long-term relief.

Most patients notice improvement within 6–12 months, with full treatment lasting around three years.

Yes, when prescribed and monitored by an ENT specialist. Most side effects are mild and temporary.

Yes, testing ensures the therapy is tailored to your specific allergens.

Children may be suitable depending on age, severity of symptoms, and specialist assessment.

Medications may be used initially and often reduced as symptoms improve.